Online Weight-Loss Programs: What to Compare in 2026

Full structural comparison

Nine factual criteria, side by side. CoreAge and Trimi are compounded-only; Pallas and Found offer brand and compounded; SkinnyRx's current verified offer is compounded-focused. For advertised prices and commitments, see the compounded GLP-1 program costs comparison.

Structural comparison of CoreAge Rx, Pallas Health, Trimi Health, Found Health, and SkinnyRx across nine factual criteria.

Criterion	CoreAge Rxprofile	Pallas Healthprofile	Trimi Healthprofile	Found Healthprofile	SkinnyRxprofile
Provider involvement	Platform (DSO Fine Shrimp LLC) plus an independent medical group (MD Integrations); a licensed clinician decides.	Platform (Brentmoor, Inc.) plus independent US-licensed clinicians (named publicly); a clinician decides.	Platform (Trimi Health) plus a stated licensed clinician network (Arora Health); a clinician decides.	Platform (Found Health, Inc.) plus affiliated medical providers; a provider decides.	Platform (Lean Rx, Inc.) plus independent providers through affiliated medical practices; a clinician decides.
Medication model	One-time or auto-renewing depending on the plan; billing policy rechecked September 9, 2026.	Recurring subscription, billed every 12 weeks.	Monthly, 3-, 6-, and 12-month plans; confirm the selected renewal terms.	CORE and PLUS care subscriptions (auto-renewal) plus separate compounded medication offers; plan families are distinct.	Auto-renewing subscription; renewal or shipment can process up to five days early.
Compounded vs FDA-approved	Compounded semaglutide and tirzepatide only, in the verified offer. Compounded is not FDA-approved.	Wegovy and Zepbound: brand, FDA-approved for weight management. Ozempic and Mounjaro: FDA-approved for type 2 diabetes, off-label for weight per a clinician. Compounded semaglutide/tirzepatide: not FDA-approved, not generics.	Compounded semaglutide and tirzepatide, in the studied offer. Compounded is not FDA-approved; no brand-name product confirmed as sold.	Brand FDA-approved (e.g. Wegovy, Zepbound) and off-label options; compounded semaglutide/tirzepatide not FDA-approved, not generics. Brand GLP-1 billed separately.	Current verified offer is compounded semaglutide/tirzepatide in injectable and tablet forms; compounded is not FDA-approved. Brand-pill availability was contradictory and is not listed as current.
Price structure (as advertised)	$99 (semaglutide) / $149 (tirzepatide), flat at every dose, supplies included. A consultation fee of $50–$100 may apply; confirm the total.	Compounded: $139 then $597/12 weeks (semaglutide); $179 then $897/12 weeks (tirzepatide), all-in. Brand-name pricing not verified.	$99/mo equivalent ($1,188 billed once yearly) for semaglutide; $125/mo equivalent ($1,500 billed once yearly) for tirzepatide. Shorter terms cost more per month.	CORE $129/30d; quarterly 2×$348 ($696/6mo); 6-month $594. PLUS $199/30d self-pay, or $39/30d / $199 a year with insurance (offer terms). Compounded semaglutide includes the medication: $99 (ins.) / $169 (cash) on a 12-month prepaid plan. Compounded tirzepatide price not shown.	From $199/mo injectable semaglutide; $249/mo semaglutide tablets; $299/mo tirzepatide options. Confirm the checkout total and commitment.
Support	Physician assessment; 24/7 provider support.	Provider visits, follow-ups, unlimited messaging, dose adjustments.	Trimi states it includes consultations, follow-ups, messaging, and dose adjustments.	Board-certified clinicians in obesity medicine; monthly check-ins; behavior-change program; AI concierge.	Independent clinician review; provider messaging and digital tracking tools.
Insurance vs self-pay	Self-pay; no insurance billing.	Cash-pay only; no insurance billing.	Cash-pay; no insurance billing. FSA/HSA per the customer’s own plan rules.	Works with select insurers; the subscription is not covered by insurance; copays/coinsurance/deductibles may apply. Surfaces the federal Medicare GLP-1 Bridge (Part D, $50 per 28–30 day supply, not guaranteed).	Cash-pay; no commercial insurance billing for the service. FSA/HSA accepted, but reimbursement is not guaranteed.
Cancellation	Cancel only before provider approval / pharmacy transmission; after that, final. Refundable treatment portion if ineligible; applicable consultation fees remain non-refundable.	Cancel anytime, effective at the end of the billing period; non-refundable once shipped.	Full refund before the prescription is issued; described as non-refundable after. Six-month guarantee has strict conditions.	Cancellation processed within 24h; subscription refund within 3 days of purchase or before the first consultation; renewals and shipped medications non-refundable.	Cancel at least five days before renewal; no partial-period refund. Orders become non-refundable after prescription fulfillment begins.
Geographic availability	No public list of states served (not verified); check availability for your state on the provider’s site.	Pallas states all 50 states and Washington, DC, subject to clinical eligibility, pharmacy coverage, and current capacity.	Operates via a multi-state clinician network; confirm availability for your state. Exact per-state availability not verified.	Availability varies by state (some states show no plans); confirm for your state. Exact per-state list not verified.	Certain compounded offers are unavailable in Alabama, Louisiana, and Mississippi; confirm current state availability.
Date verified	August 10, 2026	August 10, 2026	August 28, 2026	August 10, 2026	August 25, 2026

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